BHA Resin
(100-200 mesh, 0.3-0.8 mmol/g)

Product Catalog # SizePrice (USD) Quantity
Synonym: Benzhydrylamine Hydrochloride Salt Resin
Cross Linker (DVB): 1%
Particle Size (mesh): 100-200
Loading (mmol/g): 0.3-0.8
BHA resin has been used as solid carrier for preparation of peptide amides by Boc SPPS [1,2]. Amino acids can be attached to the support using standard amide bond-formation methods. The cleavage of the carboxylic amides from the resin requires strong acids such as trifluoromethane sulfonic acid or HF. These resins are also used as core ones for they are stable to a wide range of acidic and basic conditions.
[1] P. G. Pietta & G. R. Marshall, Chem. Commun. 1970, 650.
[2] G. Mezǒ, et al., Tetrahedron, 1998, 54, 6757
[3] G. Mezǒ, et al., J. Pept. Sci., 1999, 5, 272